Status:

COMPLETED

Weaning Children From Mechanical Ventilation:Computer-driven System Versus Usual Care

Lead Sponsor:

St. Justine's Hospital

Collaborating Sponsors:

Fonds de la Recherche en Santé du Québec

Conditions:

Respiratory Failure

Eligibility:

All Genders

2-18 years

Phase:

NA

Brief Summary

The purpose of this study is to determine whether a computer-driven system (Smartcare/PS) decreases weaning duration from mechanical ventilation when compared to usual care in children.

Detailed Description

Baseline data: All subjects included into this RCT will undergo routine examination upon admission to the hospital. These examinations include physical, medical/medication history (on the last year fo...

Eligibility Criteria

Inclusion

  • The attending physician thinks that the patient will be able to breathe spontaneously or the patients is already breathing spontaneously.
  • No vasopressor or inotropic medication, unless the patient is receiving some digitalin or small doses of dopamine (\< 5 µg/kg/min)
  • Slight or no endotracheal tube gas-leakage (\[Vti - Vte\]/Vti ≤ 20%)
  • Mechanical ventilation with a plateau pressure ≤ 25 cmH2O over PEEP
  • PEEP ≤ 8 cmH2O
  • FiO2 ≤ 60% in order to obtain pulse oxymetry ≥ 95%
  • PaCO2 \< 70 mmHg on the last blood gases
  • Extubation not expected the day of inclusion

Exclusion

  • N/A

Key Trial Info

Start Date :

September 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2009

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00678912

Start Date

September 1 2007

End Date

July 1 2009

Last Update

December 18 2025

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

CHU Sainte Justine

Montreal, Quebec, Canada, H3T 1C5