Status:

UNKNOWN

Oxford Partial Knee Replacement. A Randomized Clinical Trial of Three Implant Types

Lead Sponsor:

University of Aarhus

Collaborating Sponsors:

Aarhus University Hospital

Vejle Hospital

Conditions:

Osteoarthritis, Knee

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this scientific study is to clarify whether there is a relationship between the appearance of radiolucent lines in bone-cement interphase of the tibial component of the different models...

Detailed Description

The purpose of this scientific study is to clarify whether there is a relationship between the appearance of radiolucent lines in bone-cement interphase of the tibial component of the different models...

Eligibility Criteria

Inclusion

  • Patients, both men and women, with anteromedial unicompartmental knee osteoarthritis
  • Patients found suitable for UKA with telos stress-radiographs
  • Patients with sufficient bone quality to allow insertion of a Uni Knee prosthesis
  • Patellofemoral osteoarthritis is not a contraindication if the patient does not have symptoms from the patellofemoral joint
  • Patients can only take part in one knee study
  • All age groups, in good condition and responsible adults
  • Informed, written compliance consent.

Exclusion

  • Patients with neuromuscular or vascular diseases in the affected leg
  • Patients found to be unsuitable for UKA before or at surgery
  • Preoperative extensions defect greater than 10 degrees
  • Preoperative maximal flection of less than 100 degrees
  • Symptomatic patellofemoral osteoarthritis
  • Insufficiency with regard to ACL
  • Patients templated to a size XS or XL femoral component prior to surgery.
  • Patients with osteoporosis on the basis of preoperative x-rays or earlier diagnosis
  • Continuous medical treatment with vitamin K antagonist (Warfarin), known to reduce bone mass in general by a factor of 5
  • Patients with fracture sequelae (intraarticular fracture and all tibial condyle fractures)
  • Patients previous having PTO or other extensive knee surgery
  • Patients with metabolic bone disease
  • Patients with rheumatoid arthritis
  • Postmenopausal female patients being treated with systemic hormonal substitution (not taking into local vaginal treatment)
  • Patients who intermittently or continuously require treatment with systemic glucocorticoids
  • Non-Danish citizens
  • Insufficient command of the Danish language (read and speak)
  • Senile dementia
  • Misuse of drugs or Alcohol
  • Serious psychiatric illness
  • Disseminated malignant disease (cancer) and treatment with radiation or chemotherapy
  • Serious systemic disease (e.g.. hemiparesis and severe Parkinsonism)
  • Systemic hip or back condition
  • Employed by the department of orthopaedic surgery
  • On-going case involving work injury of the knee
  • Patients with poor dental status

Key Trial Info

Start Date :

May 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2024

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT00679120

Start Date

May 1 2009

End Date

August 1 2024

Last Update

November 22 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Orthopaedic Center, Aarhus University Hospital

Aarhus, Denmark, 8200

Oxford Partial Knee Replacement. A Randomized Clinical Trial of Three Implant Types | DecenTrialz