Status:
COMPLETED
Effect of Combined Use of Naloxone and Tramacet on Postop Analgesia in Elderly Patients Having Joint Replacement Surgery
Lead Sponsor:
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Conditions:
Hip Arthroplasty
Knee Arthroplasty
Eligibility:
All Genders
70+ years
Phase:
PHASE3
Brief Summary
Patients over 70 years of age, scheduled for joint replacement surgery will be randomized to tramacet/ naloxone plus morphine PCA or to morphine PCA to assess quality of analgesia in the postoperative...
Eligibility Criteria
Inclusion
- Aged 70 years and older\*
- Able to give informed consent
- Able to communicate in English
- Having elective hip/knee arthroplasty
- ASA physical status 1-3.
Exclusion
- Allergies to any of the following: naloxone, tramacet, NSAIDs, or local anesthetic
- Contraindication to spinal anesthesia
- Contraindication to use of tramacet or celebrex
- ASA physical status 4
- Chronic opioid use
- Chronic pain syndrome All the above will be included in the letter of information
Key Trial Info
Start Date :
December 17 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2011
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT00679614
Start Date
December 17 2007
End Date
May 31 2011
Last Update
August 28 2017
Active Locations (1)
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1
St Joseph's Health Care
London, Ontario, Canada, N6A 4V2