Status:
COMPLETED
Effect of Intraarticular Steroids on Bone Turnover in Osteoarthritis
Lead Sponsor:
University of Kansas Medical Center
Conditions:
Osteoarthritis
Eligibility:
All Genders
40-85 years
Phase:
NA
Brief Summary
Oral and nasal steroids may enhance osteoporosis by suppressing bone formation. Intra-articular steroids may also suppress bone formation, however, the duration or relationship to a steroid dose has n...
Detailed Description
Oral and nasal steroids may enhance osteoporosis by suppressing bone formation. Intra-articular steroids may also suppress bone formation, however, the duration or relationship to a steroid dose has n...
Eligibility Criteria
Inclusion
- Age \> 40 years
- Male or postmenopausal female
- Diagnosis of knee osteoarthritis
- DEXA bone density done within the past 12 months
- Painful knee, visual analogue scale (VAS) \> 4 of (10=worst)
Exclusion
- Diabetes Mellitus Type I or II
- Systemic inflammatory illness
- Systemic infections which may be aggravated by steroid therapy
- No current or previous (\< 3 years) biphosphate therapy
- Previous knee replacement surgery
- No current or previous Parathyroid hormone (PTH) therapy
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT00682357
Start Date
May 1 2008
End Date
May 1 2010
Last Update
August 13 2024
Active Locations (1)
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1
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160