Status:
COMPLETED
State Dependent Resonance in the BG-cortical Loops
Lead Sponsor:
Assistance Publique Hopitaux De Marseille
Conditions:
Parkinson Disease
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Neuronal activity in circuits between the basal ganglia (BG) and motor cortical areas is abnormally synchronized and rhythmic. The oscillatory activity prevails at 8-30 Hz in untreated Parkinson's Dis...
Detailed Description
Stimulate STN (at 0, 5, 10, 15, 20, 25, 30, 40, 70 and 130 Hz) in chronically implanted patients at rest and during simple and complex motor tasks while recording the steady state evoked potential ove...
Eligibility Criteria
Inclusion
- Parkinson's disease idiopathic evolving for more than 5 years
- Electrodes of stimulation implanted in 2 nuclei under - thalamic in the service of functional and stereotaxic neurosurgery of the CHU La timone for at least 6 months
- Doped sensibility superior to 50 % (estimated by the section III of the score UPDRS)
- Efficiency of the stimulation superior to 30 % (estimated by the section III of the score UPDRS)
Exclusion
- Patients not verifying the criteria of inclusion
- Absence of data concerning the location of electrodes
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00683566
Start Date
February 1 2008
End Date
December 1 2010
Last Update
August 28 2014
Active Locations (1)
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1
AP-HM Timone
Marseille, Bouches Du Rhone, France, 13005