Status:
COMPLETED
Specialized Clozapine Clinic for Bipolar and Schizoaffective Disorder
Lead Sponsor:
St. Joseph's Healthcare Hamilton
Conditions:
Bipolar Affective Disorder
Schizoaffective Disorder
Eligibility:
All Genders
18+ years
Brief Summary
Bipolar Disorder (BD) and Schizoaffective Disorder (SA) clients. * determine if after 12 months of treatment with clozapine, the BMI changes with clients who are councelled as usual regarding weight ...
Detailed Description
To determine whether the changes in BMI produced in subjects with Bipolar Disorder (BD) and Schizoaffective Disorder (SA) by 12 months of treatment with clozapine, can be diminished after an intense a...
Eligibility Criteria
Inclusion
- Clients diagnosed with bipolar disorder or schizoaffective disorder
- Clients who respond poorly to treatment
- Males and females ages 18 years or older
- Clients who have had a trial of antipsychotics, incl. at least one atypical antipsychotic plus at least 2 mood stabilizers
- Clients who are capable of providing informed consent
Exclusion
- Clients who take carbamazepine
- Clients with a history of extremely low white blood counts
- Clients with severe kidney, liver or heart disease, or heart operation
- Clients are hypersensitive to clozapine
- Clients who have a history of serious side effects after previous treatment with clozapine
- Clients with alcohol or drugs abuse within the last 3 months
- Clients who have a seizure disorder
- Clients who have metal in the head, neck or eyes, shrapnel, bullets, or body piercing, a pacemaker, brain aneurism clips, cochlear implant, hearing aid, tens unit, spinal implant, or pregnancy. These safety measures are necessary because of the magnetic fields of the MRI scan.
Key Trial Info
Start Date :
January 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2011
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT00683709
Start Date
January 1 2007
End Date
July 1 2011
Last Update
August 3 2011
Active Locations (1)
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1
St. Joseph's Healthcare, Centre for Mountain Health Services
Hamilton, Ontario, Canada, L8N 3K7