Status:

COMPLETED

Use of Nitazoxanide and Probiotics in Acute Diarrhea Secondary to Rotavirus

Lead Sponsor:

Centro Pediatrico Albina de Patino

Conditions:

Diarrhea

Rotavirus Infection

Eligibility:

All Genders

28-24 years

Phase:

NA

Brief Summary

Nitazoxanide has proved an cytoprotective effect against rotavirus infection. How it could be clinically important in time of hospitalization and reduction of duration of diarrhea secondary to rotavir...

Detailed Description

Nitazoxanide has demonstrated a cytoprotective effect against rotavirus, reducing duration time of diarrhea in comparison to placebo in previous studies. In the current study, based in those results, ...

Eligibility Criteria

Inclusion

  • Positive stool sample for rotavirus test

Exclusion

  • Severe malnourishment
  • Severe dehydration
  • History of diarrhea more than 3 days previous hospitalization
  • Use of antibiotics, probiotics or nitazoxanide 3 weeks before admission
  • Systemic infections
  • Severe chronic disease
  • Mixed enteric infections besides rotavirus

Key Trial Info

Start Date :

August 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2008

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT00683982

Start Date

August 1 2007

End Date

May 1 2008

Last Update

May 26 2008

Active Locations (1)

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Centro Pediatrico Albina Patiño

Cochabamba, Departamento de Cochabamba, Bolivia, 591