Status:
COMPLETED
Effect of Diacerein on Hand Osteoarthritis
Lead Sponsor:
Seoul National University Hospital
Collaborating Sponsors:
Myungmoon Pharm. Co.
Conditions:
Osteoarthritis
Eligibility:
All Genders
40+ years
Phase:
PHASE4
Brief Summary
Ostearthritis is one of the most common arthritis, affecting more than 30% of aged people world-widely. The disease is characterized by pain and stiffness of the affected joints and is the most common...
Eligibility Criteria
Inclusion
- Ages over 40 years-old
- Conforming to the classification criteria of American College of Rheumatology\*
- More than 1 tender joints
- Self reported hand pain which is more than 30 mm on the Australian/Canadian Osteoarthritis Hand Index visual analogue scales (VAS) after wash out period of 2 weeks
Exclusion
- Pregnant or lactating women
- Previous history of hypersensitivity to Diacerein
- Patients who had taken oral corticosteroid or intraarticular steroid to hand joints within 3 months of enrollment
- Patients who were injected with hyaluronic acid to hand joints within 6 months of enrollment
- Patients who underwent surgery in any joints of the hands
- AST/ALT \> 2x upper normal range
- Serum Cr \> 1.4 mg/dl
- Patients who have severe comorbidities such as severe congestive heart failure or pulmonary disease
- Patients who took oral anticoagulants.
- Patients who refuse to sign the consent form
Key Trial Info
Start Date :
June 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2009
Estimated Enrollment :
86 Patients enrolled
Trial Details
Trial ID
NCT00685542
Start Date
June 1 2008
End Date
December 1 2009
Last Update
December 3 2010
Active Locations (1)
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1
Seoul National University Hospital
Seoul, South Korea, 110-744