Status:
COMPLETED
Impact of Vaccenic Acid Consumption on the Metabolism of Saturated Fatty Acids: Relationship With Cardiovascular Risk Factors
Lead Sponsor:
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Conditions:
Cardiovascular Disease
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The investigators' project has for principal objective to evaluate the impact of three specific ruminant milk fats with a Trans Fatty Acid content ranging from 2.9% to 12.2% obtained by modification o...
Detailed Description
111 healthy, normolipemic men and women (18y to 50y) have been recruited for a monocentric, randomised, double-blind, controlled 4-week study. All the volunteers consumed 3 experimental products (butt...
Eligibility Criteria
Inclusion
- HDL cholesterol, g/L \> 0.4
- Triacylglycerol g/L \<1.50
- LDL Cholesterol g/L \<1.60
- Waist size \< 94 cm (men) or 80 cm (women)
- Affiliated to National Health Insurance
- Normal blood pressure (diastolic \<90 mm Hg, systolic \<140 mm Hg)
- For women: effective contraception
- Subject giving his/her written informed consent
- Subject willing to comply with the study procedures
Exclusion
- Reported food allergies
- Currently participating or having participated in another clinical trial during the last 4 weeks prior to the beginning of this study
- Hepatic or renal impairments
- Positive serologies to HIV or HCV,
- Blood donation done less than 2 months before the start of the study
- Chronic pathologies
- Refusal to be registered on the National Volunteers Data file
- Being in exclusion on the National Volunteers Data file
Key Trial Info
Start Date :
April 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2008
Estimated Enrollment :
107 Patients enrolled
Trial Details
Trial ID
NCT00685581
Start Date
April 1 2007
End Date
May 1 2008
Last Update
October 6 2025
Active Locations (1)
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1
Centre de Recherche en Nutrition Humaine (CRNH), UEN, Laboratoire de Nutrition Humaine
Clermont-Ferrand, France, 63009