Status:
TERMINATED
Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis
Lead Sponsor:
Mayo Clinic
Conditions:
Thumb Carpometacarpal Joint Osteoarthritis
Eligibility:
All Genders
45+ years
Phase:
NA
Brief Summary
Arthritis of the base of the thumb is a common debilitating problem. It is believed that laxity (loosening) of the joint leads to worsening arthritis in this joint. This can be treated by securing the...
Detailed Description
Dextrose prolotherapy has been shown to decrease anterior cruciate ligament (ACL) laxity and decrease knee joint pain. Similar to ACL laxity leading to knee osteoarthritis, laxity of the "beak" ligame...
Eligibility Criteria
Inclusion
- Age \>45
- Ability to make follow-up visits over the 6 month protocol
- Ability to give informed consent
- Eaton grade 2-3 thumb carpo-metacarpal joint osteoarthritis with pain over 3/10 on visual analogue scale with symptoms present greater then 6 months.
Exclusion
- Recent trauma to the hand or wrist or fractures eeen on radiographs
- Eaton grade 1, or 4 joints affected
- Metabolic bone disease
- Recent systemic or localized infection (within last 2 weeks)
- History of rheumatologic disease
- Allergies to injected solutions
- Thumb carpo-metacarpal joint injections in the prior 6 months.
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2010
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT00685880
Start Date
May 1 2008
End Date
July 1 2010
Last Update
August 30 2012
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55902