Status:
WITHDRAWN
Comparison of Abnormal Cortical Development in Brain Malformations on Postmortem Imaging With Autopsy
Lead Sponsor:
The Hospital for Sick Children
Conditions:
Brain Malformation
Eligibility:
All Genders
Brief Summary
Examination of the fetal brain at autopsy is technically challenging because of marked fragility of the brain tissue. Studies have found postmortem fetal MR to be particularly useful in examining gros...
Detailed Description
1. Autopsy will be performed at Mount Sinai Hospital according to accepted current standards, based on clinical indications. Macroscopic examination of the fetus will be performed initially, followed ...
Eligibility Criteria
Inclusion
- suspected antenatal diagnosis of brain malformation who will undergo autopsy and MRI to further assess the malformations
- above 18 weeks gestation
Exclusion
- significant autolysis of tissue specimens prior to tissue fixation
Key Trial Info
Start Date :
August 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2010
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00686530
Start Date
August 1 2007
End Date
February 1 2010
Last Update
December 3 2013
Active Locations (2)
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1
Mount Sinai Hospital
Toronto, Ontario, Canada, M5G 1X5
2
The Hospital for Sick Children
Toronto, Ontario, Canada, M5G 1X8