Status:

UNKNOWN

11C-Acetate PET/CT Non-FDG-Avid Tumors

Lead Sponsor:

Tel-Aviv Sourasky Medical Center

Conditions:

Soft Tissue Sarcomas

Thyroid Cancer

Eligibility:

All Genders

18-90 years

Brief Summary

F18-FDG is the widely used PET tracer in the routine practice of oncologic disease imaging using the technology of PET-CT. However, FDG-avidity is a characteristic of the individual tumor. There are v...

Detailed Description

Recent publications have suggested the use of 11C-acetate as another PET tracer for tumor imaging. The accumulation of 11C-acetate in tumor cells is related to the highly active lipid metabolism in th...

Eligibility Criteria

Inclusion

  • patients with newly diagnosed tumors, which are often non-FDG avid or show only low intensity uptake:
  • Soft tissue sarcomas
  • well-differentiated thyroid cancer
  • well-differentiated and bronchoalveolar lung cancer
  • indolent lymphomas
  • neuroendocrine tumors
  • GIST
  • uterine malignancies
  • mucin-producing cancer
  • teratoma
  • hepatoma
  • HCC
  • lobular breast carcinoma
  • Patients over the age of 18

Exclusion

  • patients under the age of 18 years
  • pregnant and lactating women
  • claustrophobic patients

Key Trial Info

Start Date :

May 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2010

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00687778

Start Date

May 1 2008

End Date

June 1 2010

Last Update

June 2 2008

Active Locations (1)

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1

Department of Nuclear Medicine, Tel Aviv Sourasky Medical Center

Tel Aviv, Israel, 64239