Status:

COMPLETED

Pilot Trial of a Synbiotic in HIV+ Patients

Lead Sponsor:

University of California, Davis

Conditions:

HIV Infection

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

The goal of this study is to test the hypothesis that daily ingestion of a 'synbiotic' for 4 weeks will improve intestinal function, ease immune system overactivation, and increase blood CD4 count in ...

Detailed Description

RATIONALE. HIV infection results in alterations to the intestinal tract, even in clinically healthy patients. Changes may include pronounced CD4 T-cell loss, enteric nerve and smooth muscle degenerati...

Eligibility Criteria

Inclusion

  • HIV seropositive
  • Adult Female
  • Currently taking antiretroviral medication

Exclusion

  • AIDS-defining conditions
  • Current use of oral antibiotics
  • Inflammatory bowel disease or other known GI pathology

Key Trial Info

Start Date :

May 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2009

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT00688311

Start Date

May 1 2008

End Date

November 1 2009

Last Update

November 23 2009

Active Locations (1)

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1

CARES Clinic

Sacramento, California, United States, 95811