Status:

COMPLETED

Safety and Effects of Brimonidine Intravitreal Implant in Patients With Glaucomatous Optic Neuropathy

Lead Sponsor:

Allergan

Conditions:

Glaucoma, Open-Angle

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

A multicenter, randomized, patient-masked, sham-controlled evaluation of the safety and effects on visual function of brimonidine intravitreal implant in patients with glaucomatous optic neuropathy. P...

Eligibility Criteria

Inclusion

  • Primary open-angle glaucoma in one eye
  • Visual acuity 20/80 or better
  • Intraocular pressure in the study eye ≤ 24 mm Hg
  • Glaucomatous visual field loss - 7 dB to - 25 dB

Exclusion

  • Known allergy to brimonidine tartrate
  • Uncontrolled systemic disease or infection of the eye
  • Recent eye surgery or injections in the eye
  • Female patients who are pregnant, nursing or planning a pregnancy

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2011

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT00693485

Start Date

September 1 2008

End Date

August 1 2011

Last Update

April 24 2013

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Artesia, California, United States

2

Tel Aviv, Israel