Status:

TERMINATED

Treatment for Acute Spinal Cord Injury

Lead Sponsor:

Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan

Conditions:

Spinal Cord Injury

Eligibility:

All Genders

15-60 years

Phase:

PHASE1

PHASE2

Brief Summary

This clinical trial aims to treat a damaged spinal cord by injecting your own bone marrow stromal cells (autologous bone marrow stromal cells) into cerebrospinal fluid through the lumbar puncture, and...

Eligibility Criteria

Inclusion

  • Spinal cord injury is confirmed with MRI
  • Methylprednisolone therapy according to this study can be started within 8 hours after the injury
  • Bone marrow stromal cells (BMSCs) incubation can be started within 72 hours after the injury
  • Age between 15 and 60
  • With the informed consent of obtaining bone marrow and injecting incubated BMSCs.

Exclusion

  • Complete disruption of spinal cord
  • Central spinal cord injury
  • Spinal canal stenosis before the injury
  • Brain or spinal cord disease before the injury
  • Positive serologic test in at least one of the following; HBs antigen, HCV antibody, HIV antibody, or HTLV-1 antibody
  • Pregnancy

Key Trial Info

Start Date :

July 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2010

Estimated Enrollment :

5 Patients enrolled

Trial Details

Trial ID

NCT00695149

Start Date

July 1 2005

End Date

March 1 2010

Last Update

June 2 2011

Active Locations (1)

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1

Kansai Medical University

Moriguchi, Osaka, Japan, 570-8507