Status:

COMPLETED

Efficacy and Safety Study of ARC-4558 for Management of Pain Associated With Painful Diabetic Neuropathy

Lead Sponsor:

Arcion Therapeutics Inc

Conditions:

Painful Diabetic Neuropathy

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to determine whether ARC-4558 is effective in managing pain associated with painful diabetic neuropathy.

Eligibility Criteria

Inclusion

  • has Type 1 or Type 2 diabetes mellitus
  • has a history of chronic pain attributable to a symmetrical stocking distribution neuropathy in the lower extremities for a duration of at least six months but less than or equal to five years prior to Screening

Exclusion

  • has neuropathy secondary to non-diabetic causes
  • has a significant neurological disorder or a condition that can cause symptoms that mimic peripheral neuropathy or might confound assessment of PDN
  • has other chronic pain with intensity at or greater than the bilateral pain in the feet/toes
  • is using an implanted medical device (eg, spinal cord stimulator, intrathecal pump, or peripheral nerve stimulator) for the treatment of pain
  • is pregnant or lactating

Key Trial Info

Start Date :

May 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2010

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT00695565

Start Date

May 1 2008

End Date

February 1 2010

Last Update

November 8 2016

Active Locations (16)

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Page 1 of 4 (16 locations)

1

University of Alabama at Birmingham, School of Medicine

Birmingham, Alabama, United States, 35294

2

Northern California Research

Sacramento, California, United States, 95821

3

Neurological Research Institute

Santa Monica, California, United States, 90404

4

Metabolic Research Institute

West Palm Beach, Florida, United States, 33401