Status:
WITHDRAWN
Repeated High-dose Inhaled Corticosteroids for Asthma
Lead Sponsor:
University of Chicago
Conditions:
Asthma
Eligibility:
All Genders
18-50 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to to compare the effects of high-dose Inhaled Corticosteroids (ICS) vs. placebo in adults with chronic stable asthma.
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Physician diagnosis of asthma.
- Age ≥18 years and ≤50 years
- Evidence of airflow obstruction as measured by spirometry and flow-volume loop per American Thoracic Society guidelines.
- Treatment for asthma with:
- daily inhaled corticosteroids and long-acting beta2-agonists, AND
- as-needed use of a short-acting beta2-agonist
- Exclusion criteria:
- History of \>10 pack-year tobacco use
- Other pulmonary or cardiac diagnosis that is actively being treated
- History of adverse events or allergy to fluticasone
- Systemic corticosteroid therapy within 7 days of study visit
- Inability to obtain written informed consent
Exclusion
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2011
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00695604
Start Date
May 1 2008
End Date
September 1 2011
Last Update
May 8 2018
Active Locations (1)
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1
The University of Chicago
Chicago, Illinois, United States, 60637