Status:
TERMINATED
Effects of Nitrous Oxide on Intraocular Pressure
Lead Sponsor:
Rutgers, The State University of New Jersey
Conditions:
Post Operative Visual Loss
Eligibility:
All Genders
18-65 years
Brief Summary
The concept of ocular perfusion pressure (OPP), is defined as the difference between the mean arterial pressure (MAP) and the intraocular pressure (IOP.)It has been hypothesized that unopposed decreas...
Detailed Description
Our preliminary Phase I studies using awake volunteers confirmed the increase in IOP associated with the prone position which is attenuated, although not eliminated, with a 15 cm head up table elevati...
Eligibility Criteria
Inclusion
- If I am between the ages of 18 and 65 years of age and mentally capable of giving consent.
- If I am scheduled for gynecological surgery and will be placed in the Trendelenburg position (head lower than my waist) on the operating room table.
Exclusion
- If I fail/refuse to provide an informed consent
- If I have a history of stroke or trans-ischemic attack (TIA).
- If I have a history of corneal disease.
- If I a have a sensitivity to eye drops called proparacaine
- If I have had a previous diagnosis of carotid disease.
- If I have a history of glaucoma
- If I am taking medications which may affect the pressure in my eyes
Key Trial Info
Start Date :
September 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2011
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00696189
Start Date
September 1 2006
End Date
September 1 2011
Last Update
April 24 2015
Active Locations (1)
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1
UMDNJ
Newark, New Jersey, United States, 07101