Status:
COMPLETED
Effects of Atazanavir Treatment on Type 2 Diabetes Mellitus Related Endothelial Dysfunction
Lead Sponsor:
Radboud University Medical Center
Collaborating Sponsors:
Dutch Diabetes Research Foundation
Conditions:
Type 2 Diabetes Mellitus Related Endothelial Dysfunction
Eligibility:
All Genders
18-70 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine whether atazanavir use is of influence on the endothelial dysfunction associated with type 2 diabetes mellitus.
Eligibility Criteria
Inclusion
- Inclusion Criteria (most important):
- 18 - 70 years
- type 2 diabetes mellitus treated with diet, oral medication and/or insulin
- BMI of 18 to 35
- determinants of renal and hepatic function within twice the upper limit of normal range, abnormalities in lipid profile permitted
- Exclusion Criteria (most important):
- history of smoking within past year
- history of or current abuse of drugs, alcohol or solvents
- current use of antihypertensive, cardiac or other vasoactive medication
- clinical evidence of cardiac or pulmonary disease
Exclusion
Key Trial Info
Start Date :
June 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2009
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00696722
Start Date
June 1 2008
End Date
March 1 2009
Last Update
January 26 2010
Active Locations (1)
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1
Radboud University Nijmegen Medical Centre
Nijmegen, Gelderland, Netherlands, 6500