Status:

COMPLETED

A Study to Assess the Effect of RO4607381 in Patients With Relatively Low Levels of High Density Lipoprotein-Cholesterol (HDL-C)

Lead Sponsor:

Hoffmann-La Roche

Conditions:

Dyslipidemia

Eligibility:

All Genders

18-75 years

Phase:

PHASE2

Brief Summary

This 4 arm study will evaluate the efficacy and safety of RO4607381 when co-administered with pravastatin in patients with low or relatively low HDL-C levels. Patients will be randomised to one of 4 g...

Eligibility Criteria

Inclusion

  • adult patients 18-75 years of age;
  • dyslipidemic patients with low or relatively low HDL-C levels during treatment with pravastatin.

Exclusion

  • women who are pregnant, breastfeeding, or of child-bearing potential;
  • morbid obesity;
  • uncontrolled hypertension;
  • poorly controlled or insulin-treated diabetes;
  • high creatinine levels or history of statin-associated myopathy.

Key Trial Info

Start Date :

July 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2006

Estimated Enrollment :

292 Patients enrolled

Trial Details

Trial ID

NCT00697203

Start Date

July 1 2005

End Date

May 1 2006

Last Update

January 2 2020

Active Locations (33)

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Page 1 of 9 (33 locations)

1

Mobile, Alabama, United States, 36608

2

Scottsdale, Arizona, United States, 85251

3

Newark, Delaware, United States, 19713

4

Miami, Florida, United States, 33137