Status:

COMPLETED

SEA-SIDE: Sirolimus Versus Everolimus-eluting Stent Randomized Assessment in Bifurcated Lesions and Clinical SIgnificance of Residual siDE-branch Stenosis

Lead Sponsor:

Catholic University of the Sacred Heart

Conditions:

Coronary Artery Disease

Coronary Stenosis

Eligibility:

All Genders

18-85 years

Phase:

PHASE4

Brief Summary

BACKGROUND: Bifurcated lesions are a challenging subset in percutaneous coronary interventions (PCI). The selection of the type of DES and the technique for stent implantation have not been clarified...

Detailed Description

Bifurcated lesions are challenging target lesions in percutaneous coronary interventions (PCI) which may specifically benefit from the usage of drug-eluting stents (DES). However, the selection of the...

Eligibility Criteria

Inclusion

  • de novo bifurcated lesions
  • lesions \>50% located in a major bifurcation point
  • TIMI \>2 on both main vessel and side branch
  • main vessel visual diameter \>2.5 mm
  • side branch visual diameter \>2.0 mm
  • \>18 years of age
  • signed the informed consent to enter the study

Exclusion

  • known hypersensitivity to Sirolimus, Everolimus, cobalt, chromium, nickel, tungsten acrylic and fluoro-polymers
  • contraindications to double antiplatelet therapy acute (within 48 hours) ST-elevation acute myocardial infarction

Key Trial Info

Start Date :

September 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2010

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT00697372

Start Date

September 1 2007

End Date

April 1 2010

Last Update

June 15 2010

Active Locations (1)

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Institute of Cardiology - Catholic University of Sacred Heart

Rome, Italy, 00168