Status:
COMPLETED
Circadian Rhythm of Erythropoietin And Melatonin in Renal Disease
Lead Sponsor:
Meander Medical Center
Collaborating Sponsors:
Stichting Bijstand, Meander Medical Center
Hoffmann-La Roche
Conditions:
Chronic Kidney Disease
Eligibility:
All Genders
18-85 years
Brief Summary
Rationale: Investigation of the circadian rhythm of erythropoietin and melatonin in patients with various degrees of renal insufficiency Objectives: Primary objective: Is there a circadian rhythm of...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Patient with various degrees of renal insufficiency, stable creatinin clearance: minimum 10 ml/min (measured with MDRD), admitted to our hospital
- Informed Consent
- Man/Women between 18 and 85 years
- Understanding and knowledge of the dutch language
- Exclusion criteria:
- Instable angina pectoris, heart failure NYHA class IV
- Therapy with erythropoetin, melatonin and hypnotics
- Acute renal failure or rapidly progressive glomerulonephritis
- Bleeding or hemolysis as a cause of anemia
- Deficiency of iron, folate and/or vitamin B12
- Presence of chronic inflammatory disease or clinically significant infection
- Hemoglobinopathies
- Alcohol and/or drug abuse
- Enrolment in another study
- Any kind of disorder that compromises the ability of the subject to give written informed consent and/or to comply with study procedures
Exclusion
Key Trial Info
Start Date :
July 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2008
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT00698360
Start Date
July 1 2007
End Date
June 1 2008
Last Update
June 17 2008
Active Locations (1)
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1
Meander Medical Center
Amersfoort, Netherlands, 3818 ES