Status:
COMPLETED
Treatment Study: Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine (ARC)
Lead Sponsor:
Wayne State University
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Heroin Dependence
Opioid-Related Disorders
Eligibility:
All Genders
18-55 years
Brief Summary
This research study takes place at Wayne State University and will take about 11 weeks to complete. This is a treatment research study for individuals who currently have cocaine abuse or dependence, a...
Detailed Description
Cocaine dependence, particularly in combination with heroin dependence, poses serious and substantial public health, social, and economic problems (e.g., high medical costs, crime, lost productivity)....
Eligibility Criteria
Inclusion
- Male or non-pregnant and non-lactating females between 18-55 years of age who are seeking treatment for their drug use.
- Females of childbearing potential are eligible to participate if using an acceptable method of birth control.
- All participants must be free from any significant clinical abnormalities based on medical history, physical examination, ECG, and screening laboratory tests.
- Participants must weigh at least 50kg (110lbs).
- Participants must meet DSM-IV criteria for current Cocaine Abuse or Dependence, and possibly Opioid Dependence, and provide a cocaine positive (and, if opioid dependent, opioid positive) urine sample.
- Participants will not be excluded if they meet DSM-IV criteria for current Alcohol or Sedative Abuse (but they will be excluded for current Alcohol or Sedative Dependence).
- Participants must not be under the influence of alcohol (BAL \<.002) and sign informed consent during screening.
Exclusion
- Volunteers will not be eligible for this study if they present with psychiatric illness, neurological disease, cardiovascular disease, pulmonary disease, systemic disease, other current substance dependence (except cocaine, heroin or nicotine).
- If they are cognitively impaired, currently being treated for Cocaine or Opioid Dependence, using prohibited medications, or females who are pregnant, lactating, or if heterosexually active not using medically approved birth control measures.
Key Trial Info
Start Date :
April 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2012
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT00698737
Start Date
April 1 2008
End Date
November 1 2012
Last Update
November 22 2012
Active Locations (1)
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1
Wayne State University
Detroit, Michigan, United States, 48202