Status:
COMPLETED
Evaluation of a New Mechanical Ventilation Weaning Strategy for Patients With Altered Level of Consciousness
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Artificial Respiration
Consciousness Disorders
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
The purpose of this study is to determine if a weaning strategy from artificial ventilation governs by respiratory behaviour status assessed by our method is safe enough.
Detailed Description
Current guidelines for mechanical ventilation weaning do not apply for patients with altered level of consciousness. One major limitation is a failure of clinical assessment of the respiratory behavio...
Eligibility Criteria
Inclusion
- Altered level of consciousness (-1 \< RASS \> +1)
- Mechanical ventilation ( \> 72 hours)
- Withdrawal of sedative drugs (\> 48 hours)
- T tube challenge tolerance
- Signed approval for the study by close relative or legal representative
Exclusion
- Respiratory disease prior to the actual artificial ventilation requirement.
- Impairment of upper airway function prior to the actual artificial ventilation requirement.
- Pregnancy
- Minor
Key Trial Info
Start Date :
April 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2011
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT00700869
Start Date
April 1 2008
End Date
September 1 2011
Last Update
October 5 2011
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Anesthesia and CCM; Lariboisière Hospital
Paris, France, 75010