Status:
UNKNOWN
Management of Patients With Alpha-1 Antitrypsin Deficiency Associated Emphysema
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Alpha 1-Antitrypsin Deficiency
Emphysema
Eligibility:
All Genders
18+ years
Brief Summary
The aim of this study is to describe the natural history of patients with alpha-1 antitrypsin associated emphysema and to figure out associated prognostic factors.
Detailed Description
All patients who suffer from this disease are followed every 6 months during a 5 years period. FEV1 decline is the primary endpoint. Quality of life assessed using the Saint George's Respiratory Quest...
Eligibility Criteria
Inclusion
- Serum alpha one antitrypsin \< 0.8 g/l
- Emphysema diagnosed by CT scan
- Adult
- Obstructive disorder
Exclusion
- Liver or lung transplantation
Key Trial Info
Start Date :
February 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 1 2012
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT00700934
Start Date
February 1 2005
End Date
February 1 2012
Last Update
December 7 2010
Active Locations (1)
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1
Departement d'épidémiologie, Hôpital Bichat
Paris, France, 75018