Status:
COMPLETED
Exercise Training and Glucose Metabolism in Aging
Lead Sponsor:
US Department of Veterans Affairs
Collaborating Sponsors:
University of Maryland
National Institutes of Health (NIH)
Conditions:
Type 2 Diabetes Mellitus
Impaired Glucose Tolerance (Prediabetes)
Eligibility:
All Genders
50-75 years
Phase:
NA
Brief Summary
Diabetes and its associated complications affect more than 20 million Americans, and the prevalence of type 2 diabetes and impaired glucose tolerance rises dramatically with age such that 40% of Ameri...
Eligibility Criteria
Inclusion
- Age 50-75 years
- Non-smoker \>2 years
- Body mass index = 18-35 kg/m2
Exclusion
- History of CAD or cerebrovascular disease that would preclude exercise
- Implantable defibrillator
- Active cancer
- Chronic pulmonary, thyroid, renal, liver, or hematological disease
- HIV positive or prone to malnutrition
- Sickle cell anemia
- Type 1 diabetes, or currently on medication to treat type 2 diabetes
- Poorly-controlled type 2 diabetes
- Poorly-controlled hypertension
- Taking medications including: beta-blockers, oral steroids, warfarin, certain statins, hormone replacement therapy (HRT), oral contraceptives (OCP), thiazolidinediones (TZD), or chronic steroids or nonsteroidal analgesics (NSAIDS) that may not be safely discontinued temporarily for specific procedures (i.e. for 72 hours prior)
- Allergic to lidocaine or heparin
- Recent weight change (\>5kg in 3 months)
- Currently pregnant or nursing
- Physical impairment limiting exercise
- Dementia or unstable clinical depression
Key Trial Info
Start Date :
October 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT00701051
Start Date
October 1 2006
End Date
June 1 2012
Last Update
April 6 2015
Active Locations (1)
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1
VA Maryland Health Care System, Baltimore
Baltimore, Maryland, United States, 21201