Status:

COMPLETED

Study to Evaluate the Safety, Tolerability, and Blood Pressure Effect of an Oral Dose of Sumatriptan Alone and in Combination With MK-0974 (Telcagepant) in Migraine Patients (0974-026)

Lead Sponsor:

Merck Sharp & Dohme LLC

Conditions:

Migraine Disorders

Eligibility:

All Genders

18-65 years

Phase:

PHASE1

Brief Summary

Study to understand the effects of migraine treatments on blood pressure in participants with migraine. The primary hypothesis is that the effect on semi-recumbent mean arterial pressure following the...

Eligibility Criteria

Inclusion

  • History of migraine for longer than 6 months.
  • Free from migraine 24 hours before each dosing.
  • Judged to be in good health.
  • Nonsmoker

Exclusion

  • Under age of legal consent.
  • Legally or mentally incapacitated or has significant emotional problems.
  • Taking any medications from about 2 weeks before the first dose of study medication.
  • Has had surgery or donated blood or participated in another investigation study within 4 weeks prior to screening
  • Currently a regular user of any illicit drugs or has a history of drug/alcohol abuse within about 2 years
  • Consumes more than 6 caffeinated beverages per day

Key Trial Info

Start Date :

November 20 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 10 2008

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT00701389

Start Date

November 20 2007

End Date

April 10 2008

Last Update

October 17 2018

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Study to Evaluate the Safety, Tolerability, and Blood Pressure Effect of an Oral Dose of Sumatriptan Alone and in Combination With MK-0974 (Telcagepant) in Migraine Patients (0974-026) | DecenTrialz