Status:
COMPLETED
Ontogenesis of the P-Glycoprotein in Human Lymphocytes Influence of HIV and Antiretroviral Therapeutics
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
HIV Infections
Eligibility:
All Genders
Brief Summary
The P-glycoprotein (P-gp) is a membranous transporter that modulates the intracellular concentrations of many drugs and plays thus a major role in the efficacy of the therapeutics that act within the ...
Detailed Description
Several groups of drugs involved in the treatment of major pathologies act within the lymphocyte, such as anticancer, immunosuppressive and antiretroviral drugs. These molecules depend on membranous t...
Eligibility Criteria
Inclusion
- age, HIV status
Exclusion
- None
Key Trial Info
Start Date :
March 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2009
Estimated Enrollment :
310 Patients enrolled
Trial Details
Trial ID
NCT00702013
Start Date
March 1 2007
End Date
August 1 2009
Last Update
November 11 2010
Active Locations (1)
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1
Hopital Necker Enfants Malades
Paris, France, 75015