Status:
UNKNOWN
Telmisartan Versus Ramipril After Acute Coronary Syndrome
Lead Sponsor:
Catholic University of the Sacred Heart
Conditions:
Acute Coronary Syndrome
Myocardial Infarction
Eligibility:
All Genders
40-80 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to compare the antinflammatory and endothelial progenitor cell (EPC) mobilizing effect of Ramipril and Telmisartan in patients presenting with acute coronary syndrome
Eligibility Criteria
Inclusion
- Biochemical evidence of myocardial infarction as indicated by elevation of cTnT,
- presence of ECG ischemic changes,
- angiographic evidence of a primary coronary event, such as plaque erosion and/or rupture, fissuring, or dissection at coronary angiography,
- successful coronary revascularization of at least one culprit coronary vessel.
Exclusion
- Age\>80 years, current ACE inhibitor or ARB treatment,
- ejection fraction \<35%, infarction secondary to ischemia due to an imbalance of O2 supply and demand,
- ECG abnormalities that could affect the recognition of ST segment shift,
- recent or chronic infective or inflammatory diseases,
- malignancy, and myocardial infarction,
- surgery or trauma in the previous month.
Key Trial Info
Start Date :
November 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2008
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00702936
Start Date
November 1 2007
End Date
November 1 2008
Last Update
June 20 2008
Active Locations (1)
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1
Catholic University of the Sacred Heart
Rome, Italy, 00168