Status:

COMPLETED

To Evaluate Sperm Parameters in Men With Secondary Hypogonadism Previously Treated With Topical Testosterone

Lead Sponsor:

Repros Therapeutics Inc.

Conditions:

Secondary Hypogonadism

Eligibility:

MALE

21-60 years

Phase:

PHASE2

Brief Summary

The study was designed to determine if Androxal® would affect sperm parameters (count, concentration, volume) in men with secondary hypogonadism who have been previously treated with topical testoster...

Detailed Description

The study was designed to determine if Androxal® would affect sperm parameters (count, concentration, volume) in men with secondary hypogonadism who have been previously treated with topical testoster...

Eligibility Criteria

Inclusion

  • Healthy adult males between 21 and 60 years of age who have been diagnosed with AIHH.
  • Subjects must have been treated with a topical testosterone replacement therapy (typically AndroGel® or Testim®) for at least 6 months at enrollment and for not more than 2 years.

Exclusion

  • A history of idiopathic infertility due to primary hypogonadism, testicular failure, Kallmann's syndrome or any other infertility condition.
  • Subjects demonstrating any clinically significant medical condition rendering the subjects infertile or marginally fertile other than AIHH.
  • Men with a history of, known, or suspected prostate disease not ruled out by a prostate biopsy, or a prostate specific antigen (PSA)\>3.6 or clinical suspicion of current prostate disease.
  • Men with a hematocrit in excess of 50 % or hemoglobin \>17 g/dl

Key Trial Info

Start Date :

June 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2009

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT00706719

Start Date

June 1 2008

End Date

August 1 2009

Last Update

August 19 2015

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University Urology Associates

New York, New York, United States, 10016

2

MAZE Labs

Purchase, New York, United States, 10577