Status:
COMPLETED
Evaluation of ST2 and IL-33 in Patients Presenting to the Emergency Department With Trouble Breathing
Lead Sponsor:
The Cleveland Clinic
Collaborating Sponsors:
Critical Diagnostics
Conditions:
Chronic Obstructive Pulmonary Disease
Asthma
Eligibility:
All Genders
18+ years
Brief Summary
Trouble breathing (dyspnea) is a nonspecific symptom associated with many diseases such as chronic obstructive pulmonary disease (lung disorder in which the flow of air to the lungs is blocked), asthm...
Eligibility Criteria
Inclusion
- Presenting to the Emergency Department with signs and symptoms of dyspnea (short of breath, tachypnea, hyperventilation, etc) within the last 24 hours
- Normal cardiac output as measured by noninvasive bioimpedance
- Greater than or equal to 18 years of age
- Patient or legal representative willing and able to provide informed consent and comply with study procedures
Exclusion
- ECG changes diagnostic of acute myocardial ischemia/infarction
- Ischemic chest pain within the prior 24 hours by history
- Obvious chest trauma
- Exclusion Criteria for Blood Draw:
- A history of congestive heart failure and a BNP \> 500pg/mL (or NTproBNP \> 900pg/mL) if obtained by the treating physician
- Treating physician suspects patient has new onset congestive heart failure
Key Trial Info
Start Date :
April 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2010
Estimated Enrollment :
82 Patients enrolled
Trial Details
Trial ID
NCT00707811
Start Date
April 1 2008
End Date
June 1 2010
Last Update
March 20 2024
Active Locations (1)
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1
The Cleveland Clinic
Cleveland, Ohio, United States, 44195