Status:
TERMINATED
Neurotoxicity in Primary Central Nervous System Lymphoma (PCNSL): An International Observational Study of Cognition in Long Term Survivors
Lead Sponsor:
OHSU Knight Cancer Institute
Collaborating Sponsors:
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Primary Central Nervous System Lymphoma (PCNSL)
Eligibility:
All Genders
18-75 years
Brief Summary
This research is being done to investigate cognition in long term survivors of Primary Central Nervous System Lymphoma (PCNSL). Sometimes caregivers as well as patients who no longer have the disease ...
Detailed Description
This is an international, multi-center project that will enroll as many as 118 subjects of which approximately 35 will be enrolled at Oregon Health \& Science University (OHSU). Neuropsychological tes...
Eligibility Criteria
Inclusion
- Radiological and histological diagnosis of PCNSL
- Age 18 years or older
- Survived 2 years or more following treatment
- Able to complete neuropsychological and neuroimaging parts of the study
- Signed a written informed consent in accordance with institutional guidelines
Exclusion
- Subject has experienced recurrent disease
- Subject has a contraindication for MRI
- Subject has a contraindication for neuropsychological testing
- Subject has stage IV or V renal insufficiency
Key Trial Info
Start Date :
July 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00710151
Start Date
July 1 2008
End Date
December 1 2013
Last Update
April 21 2017
Active Locations (4)
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1
Oregon Health & Science University
Portland, Oregon, United States, 97239
2
Charite University Medicine
Berlin, Germany
3
University of Bochum
Bochum, Germany
4
University Medical Center
Freiburg im Breisgau, Germany