Status:
COMPLETED
Role of Leukotrienes and Adenosine in Hyperpnea-induced Bronchospasm
Lead Sponsor:
University of Vermont
Conditions:
Asthma, Exercise Induced
Eligibility:
All Genders
12-75 years
Brief Summary
This research is being conducted to help us better understand what causes exercise induced asthma. The investigators hypothesize that two types of chemicals, cysteinyl leukotrienes and adenosine, play...
Eligibility Criteria
Inclusion
- Physician diagnosed asthma
- Age 12-75 yrs
- FEV1 \> 70% predicted
- HIB response \> 10 %
- No smoking last 6 mo and \< 10 pack yrs
- No URI last 4 weeks
- No asthma exacerbation last 4 weks
- Able to withhold SABA \> 8 hrs and LABA \> 24 hrs
Exclusion
- Other lung disease
- Cardiac disease or other condition that would preclude safe participation, on theophylline or leukotriene modifiers
Key Trial Info
Start Date :
October 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2009
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT00710255
Start Date
October 1 2007
End Date
July 1 2009
Last Update
October 31 2016
Active Locations (1)
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1
Vermont Lung Center
Colchester, Vermont, United States, 05446