Status:

COMPLETED

Topical Vancomycin in Prevention of Methicillin-Resistant Staphylococcal Related Mediastinitis in Patients Receiving Coronary Artery Bypass Graft

Lead Sponsor:

Far Eastern Memorial Hospital

Conditions:

Coronary Artery Disease

Eligibility:

All Genders

20+ years

Phase:

NA

Brief Summary

Sternal or mediastinal infections after heart operation occurs infrequently but carries a high cost in money, morbidity, and mortality. At our hospital, Staphylococcus species cause most of these infe...

Detailed Description

Background Postoperative sterno-mediastinitis is a life-threatening complication. Although the incidence rate is about 0.75 to 1.4% in all open heart operations, the association with morbidity, mortal...

Eligibility Criteria

Inclusion

  • Patients with coronary artery disease underwent aoronary artery bypass grafting

Exclusion

  • Patients who ever received vancomycin or teicoplanin or linezolids within one week will be excluded. Other exclusion criteria are patients in pregnant, allergic to vancomycin, and hesitate to this study plan.

Key Trial Info

Start Date :

January 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00711685

Start Date

January 1 2007

Last Update

July 9 2008

Active Locations (1)

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Far Eastern Memorial Hospital

Taipei, Taiwan