Status:

UNKNOWN

Use of Cold and Compression Therapy With Total Knee Replacement Patients

Lead Sponsor:

CoolSystems, Inc.

Conditions:

Osteoarthritis

Total Knee Arthroplasty

Eligibility:

All Genders

18-85 years

Phase:

PHASE4

Brief Summary

The purpose of the study is to evaluate the effectiveness of a device that delivers cold and intermittent compression as compared to ice and compressive wraps on patients who have undergone knee repla...

Detailed Description

The use of cryotherapy with compression for orthopedic postoperative recovery has not been fully investigated. A new device has been developed that combines cold and intermittent pneumatic compression...

Eligibility Criteria

Inclusion

  • At least 18 but no more than 85 years of age
  • Body Mass Index not greater than 40
  • Diagnosis of osteoarthritis of the knee
  • Medically cleared for total knee replacement surgery
  • Physically and mentally able and willing to participate in and follow the study protocol and schedule
  • Able and willing to have all postoperative physical therapy visits in a physical therapy clinic associated with the research site
  • Signed informed consent document for the study

Exclusion

  • Rheumatoid arthritis
  • Severe pitting edema in the ipsilateral limb
  • History of thrombophlebitis in lower extremities
  • An active systemic disease such as AIDS, HIV, hepatitis, etc.
  • Is immunologically suppressed or has received or is receiving steroids at any dose daily for more than one month within the last 12 months
  • Is pregnant or planning to become pregnant during the study period
  • Any condition that would contraindicate using the Game Ready
  • Currently enrolled in another clinical trial that could affect outcome of this study
  • Previously enrolled in this study

Key Trial Info

Start Date :

July 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2012

Estimated Enrollment :

224 Patients enrolled

Trial Details

Trial ID

NCT00712816

Start Date

July 1 2008

End Date

May 1 2012

Last Update

March 20 2012

Active Locations (11)

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Page 1 of 3 (11 locations)

1

Naval Medical Center, San Diego

San Diego, California, United States, 92134

2

Tripler Army Medical Center

Honolulu, Hawaii, United States, 96859

3

Central DuPage Hospital

Winfield, Illinois, United States, 60190

4

Orthopaedic Research Foundation

Indianapolis, Indiana, United States, 46278