Status:
UNKNOWN
Alfuzosin for Medical Expulsion Therapy of Ureteral Stones
Lead Sponsor:
United States Naval Medical Center, San Diego
Conditions:
Kidney Stones
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The goal of this study is to conduct a prospective controlled trail of four currently approved Department of Defense (DOD) - formulary medications for use as medical expulsion therapy (MET) for kidney...
Detailed Description
Patients presenting to Naval Medical Center San Diego with symptomatic ureteral stones visible on CT and KUB, and who are medically stable will be offered enrollment. Upon consent, patients will be ra...
Eligibility Criteria
Inclusion
- Age \>/= 18 years
- Single ureteral stone \< 1 cm in greatest dimension
Exclusion
- Age \< 18 years
- Active unstable angina
- History of or active postural hypotension (\>20 mmHg drop in orthostatic SBP)
- Allergy to alpha-blockers
- Acute or Chronic Renal Failure as demonstrated by a serum creatinine of \> 1.4 mg/dl
- Urinary tract infection
- Multiple ureteral stones
- Current uncontrolled diabetes
- Alpha-blocker therapy within 30 days for any reason
- Current pregnancy or lactation
- Patient desire for immediate stone removal
Key Trial Info
Start Date :
January 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2012
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT00713739
Start Date
January 1 2008
End Date
December 1 2012
Last Update
April 27 2012
Active Locations (1)
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1
Naval Medical Center San Diego
San Diego, California, United States, 92134