Status:

COMPLETED

Renal Blood Flow Measurement With Positron Emission Tomography (PET)

Lead Sponsor:

Jeffrey L. Lacy

Collaborating Sponsors:

University of Wisconsin, Madison

Conditions:

Renal Failure

Renal Artery Stenosis

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Two investigational chemical tracers, 62Cu-ethylglyoxal bis(thiosemicarbazone) (62Cu-ETS) and 15O-water, will be used in this study to look at how blood moves through the kidneys. The purpose of the s...

Eligibility Criteria

Inclusion

  • Arm 1.
  • males and females, age 18-40 years
  • willingness to provide written informed consent

Exclusion

  • history of coronary artery disease (CAD)
  • history of renal disease
  • risk factors for cardiac disease, renal disease, or atherosclerosis, including diabetes mellitus, hypertension, tobacco abuse, hyperlipidemia, family history of CAD or chronic renal failure
  • history of liver disease or other significant disease
  • pregnant females
  • Arm 2.
  • Inclusion Criteria:
  • males and females, age \> 18 years
  • active hemodialysis or peritoneal dialysis for at least six months
  • any etiology of chronic renal failure except active glomerular nephritis
  • presence of two kidneys
  • willingness to provide written informed consent

Key Trial Info

Start Date :

August 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2009

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00714142

Start Date

August 1 2008

End Date

April 1 2009

Last Update

April 19 2017

Active Locations (1)

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1

University of Wisconsin - Madison

Madison, Wisconsin, United States, 53792