Status:

UNKNOWN

Determination of Predictive Value of Echography Doppler Abnormalities

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Conditions:

Breast Cancer

Upper Extremity Deep Vein Thrombosis, Secondary

Eligibility:

FEMALE

18-80 years

Brief Summary

In order to avoid to use a traumatic and iatrogenic examen (phlebography), the purpose of the study is to validate echography doppler in the diagnosis of asymptomatic related catheter related thrombos...

Detailed Description

Phlebography is the gold standard for the diagnosis of asymptomatic catheter related thrombosis but can not be performed in about 15% of patients because of arm swelling and lack of superficial veins....

Eligibility Criteria

Inclusion

  • women over 18
  • histologically proven breast cancer
  • localized breast cancer without metastasis
  • adjuvant or neo adjuvant chemotherapy
  • insertion of central catheter with port for chemotherapy
  • central catheter for more than three months
  • inform consent
  • follow up for three months

Exclusion

  • ongoing anticoagulant therapy
  • previous central catheter
  • femoral catheter
  • double lumen catheter
  • central catheter without port
  • platelets \< 80G/L, TQ \< 50%, fibrinogen \< 1 g/L
  • creatinin \> 175mole/L

Key Trial Info

Start Date :

November 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2012

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT00714909

Start Date

November 1 2008

End Date

May 1 2012

Last Update

February 23 2011

Active Locations (1)

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1

Saint-Louis Hospital

Paris, France, 75010