Status:
COMPLETED
Transitioning Open Heart Surgery Patients From Insulin Infusions to Detemir
Lead Sponsor:
Ohio State University
Collaborating Sponsors:
Novo Nordisk A/S
Conditions:
Diabetes Mellitus
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
In this study we will determine the proper method for transitioning patients from a continuous insulin infusion to periodic injections of a newer long-acting insulin called detemir (Levemir).
Detailed Description
High sugar (glucose) is common after surgery, even in patients who do not have diabetes. High glucose contributes to severe hospital complications and even death. Insulin infusions appear to reduce th...
Eligibility Criteria
Inclusion
- diabetes mellitus
- post-cardiothoracic surgery
- requiring an insulin infusion of at least 1 unit/hour
- Age 18-75
Exclusion
- Glucocorticoids
- total parenteral nutrition (TPN) or tube feeds
- Pregnancy
- Surgical procedures in the next 48 hours for whom intravenous (IV) insulin will be expected
- Expected length of stay less than 48 hours following cessation of the insulin drip
- Patients using subcutaneous insulin pumps
- Diabetic ketoacidosis
- End-stage renal disease
- End-stage liver disease
- Coma
- Potentially sensitive admissions: prisoners, human immunodeficiency virus(HIV), suicidality
- Unable to give consent in English
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2010
Estimated Enrollment :
82 Patients enrolled
Trial Details
Trial ID
NCT00717288
Start Date
July 1 2008
End Date
June 1 2010
Last Update
October 3 2011
Active Locations (1)
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1
The Ohio State University
Columbus, Ohio, United States, 43210