Status:
COMPLETED
T Regulatory Cells in Renal Cell Carcinoma (PILOT STUDY)
Lead Sponsor:
National University Hospital, Singapore
Conditions:
Renal Cell Carcinoma
Eligibility:
All Genders
21+ years
Brief Summary
To define the frequency of T regulatory cells in peripheral blood of RCC patients before and after nephrectomy. Study hypothesis: That nephrectomy results in a normalisation of peripheral blood T reg...
Detailed Description
T regulatory cells (T regs) are a recently identified subset of T cells with inhibitory functions on the immune system. In cancer, it has been shown that there is an increased proportion of T regs in ...
Eligibility Criteria
Inclusion
- Subjects must meet all of the inclusion criteria to participate in this study:
- Diagnosed Renal Cell Carcinoma patients for whom nephrectomy is planned or scheduled as treatment. (Preoperative histologic diagnosis is not required.)
- All stages of disease are eligible.
- Adult patients above 21.
- Ability to provide informed consent
Exclusion
- Subjects meeting any of the exclusion criteria at baseline will be excluded:
- Active infection.
- Immunocompromised or other active immune disorders.
- Not on any immunomodulating therapy.
Key Trial Info
Start Date :
March 1 2007
Trial Type :
OBSERVATIONAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00717743
Start Date
March 1 2007
Last Update
April 9 2010
Active Locations (1)
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1
National University Hospital
Singapore, Singapore