Status:

COMPLETED

Molecular Analysis of Retinoblastoma

Lead Sponsor:

St. Jude Children's Research Hospital

Collaborating Sponsors:

National Eye Institute (NEI)

Conditions:

Retinoblastoma

Eligibility:

All Genders

Brief Summary

Retinoblastoma is a childhood tumor of the retina that affects approximately 1 in 18,000 children. Retinoblastoma is more prevalent in Central America, where most patients present with advanced intrao...

Detailed Description

This is a biology protocol with no treatment regimen associated. Following routine enucleation of the retinoblastoma affected eye, a portion of the tumor will be removed and flash frozen and sent to S...

Eligibility Criteria

Inclusion

  • Must have clinical diagnosis of retinoblastoma (to be confirmed histologically after enucleation)
  • Legal guardians must willing to sign an informed consent indicating that they are aware of this study and its possible benefits. Legal guardians will be given a copy of the consent form.
  • Patient is being seen at this AHOPCA institution:

Exclusion

  • Ophthalmologist or oncologist is concerned that sampling will interfere with staging.
  • Diagnosis other than retinoblastoma.
  • Affiliated hospital is unable to provide pathologic evidence of retinoblastoma.

Key Trial Info

Start Date :

April 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2016

Estimated Enrollment :

41 Patients enrolled

Trial Details

Trial ID

NCT00718783

Start Date

April 1 2007

End Date

December 1 2016

Last Update

December 14 2016

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Hospital Calvo Mackenna

Santiago, Santiago Metropolitan, Chile

2

Hospital Escuela Bloque Materno Infantil

Tegucigalpa, Honduras