Status:
COMPLETED
Impact of In-centre Nocturnal Hemodialysis on Ventricular Remodeling and Function in End-stage Renal Disease
Lead Sponsor:
Unity Health Toronto
Collaborating Sponsors:
Canadian Institutes of Health Research (CIHR)
Conditions:
End-stage Renal Disease
Left Ventricular Hypertrophy
Eligibility:
All Genders
18+ years
Brief Summary
Background: Recent data indicate that home nocturnal hemodialysis (8 hours of hemodialysis at home for 5-6 nights per week) may have substantial cardiovascular benefits, including regression of left v...
Eligibility Criteria
Inclusion
- adult patients currently treated with conventional hemodialysis for \> 6 months
Exclusion
- acute coronary syndrome or coronary revascularization (percutaneous coronary intervention, coronary bypass surgery) within the past 6 months
- uncontrolled hypertension (systolic blood pressure \> 200 mmHg, or diastolic blood pressure \> 120 mmHg)
- severe heart failure (New York Heart Association functional class IV)
- chronic atrial fibrillation
- serious co-morbidity (e.g. cancer) with a life expectancy of less than 1 year
- pregnancy
- patient refusal to undergo baseline CMR
- contraindications to CMR (e.g. pacemaker, implantable cardiac defibrillator)
- inability to provide informed consent
Key Trial Info
Start Date :
July 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
67 Patients enrolled
Trial Details
Trial ID
NCT00718848
Start Date
July 1 2008
End Date
December 1 2012
Last Update
October 14 2015
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
St. Paul's Hospital
Vancouver, British Columbia, Canada, V6Z 1Y6
2
St. Michael's Hospital
Toronto, Ontario, Canada, M5B 1W8