Status:

COMPLETED

AVN of Weight-Bearing Joints In Patients With Hematologic Malignancies Treated With Dexamethasone Or Prednisone

Lead Sponsor:

St. Jude Children's Research Hospital

Conditions:

Avascular Necrosis

Acute Lymphoblastic Leukemia

Eligibility:

All Genders

Brief Summary

The primary purpose of this study is to compare the incidence of AVN in children with hematologic malignancies treated with prednisone versus dexamethasone during continuation.

Detailed Description

Patients with acute lymphoblastic leukemia enrolled on the St. Jude Children's Research Hospital front-line Acuter Lymphoblastic Leukemia protocol, Total XIIIB or the front-line Non Hodgkin's Lymphoma...

Eligibility Criteria

Inclusion

  • Patients with acute lymphoblastic leukemia enrolled on the SJCRH front-line ALL protocol, TOTAL XIIIB or the front-line NHL protocol NHL13 from 11/94 to 6/98.
  • Patients must be in continuous complete remission or have an MRI-confirmed diagnosis of AVN of the hip or knee prior to relapse.

Exclusion

  • \-

Key Trial Info

Start Date :

July 1 2001

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 1 2005

Estimated Enrollment :

170 Patients enrolled

Trial Details

Trial ID

NCT00719147

Start Date

July 1 2001

End Date

July 1 2005

Last Update

September 27 2011

Active Locations (1)

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St. Jude Children's Research Hospital

Memphis, Tennessee, United States, 38105