Status:

COMPLETED

Study to Assess the Efficacy of Cognitex

Lead Sponsor:

Tel-Aviv Sourasky Medical Center

Collaborating Sponsors:

Enzymotec

Conditions:

Elderly

Memory Impairment

Eligibility:

All Genders

60-90 years

Phase:

PHASE4

Brief Summary

A Single-Center, Open Label Study to Assess the Efficacy of Cognitex in Elderly Subjects with Memory Impairment

Eligibility Criteria

Inclusion

  • Ability to give written informed consent.
  • Age: 90≥ years ≥60.
  • Gender: male and female.
  • Memory test performance within or below the mean established for adults in the computerized cognitive tool, with a maximum of four neuropsychological subtests scored 1.5 SD above the mean.
  • Language: Subjects must be able to read, write and speak Hebrew.
  • Ability to perform tests and interviews.

Exclusion

  • Evidence of delirium, confusion, or other disturbances of consciousness.
  • Evidence of dementia.
  • Any Neurological disorder that could produce cognitive deterioration. Such disorders include Parkinson's disease, stroke, intracranial hemorrhage, local brain lesions including tumors and normal pressure hydrocephalus.
  • History of any infective or inflammatory brain disease including those of viral, fungal, or syphilitic etiologies.
  • Head injury immediately preceding cognitive deterioration.
  • Evidence of depression as determined by a the Geriatric Depression Scale (short version) score of 5 or more.
  • Current diagnosis or history of alcoholism or drug dependence.
  • Any medical disorder that could produce cognitive deterioration including renal, respiratory, cardiac, and hepatic disease, diabetes mellitus, endocrine, metabolic or hematological disturbances unless well controlled, and malignancy not in remission for more than two years
  • Use of anti-clotting or antiplatelet medications or supplements for less than two years.
  • History of clotting or platelet disorder unless well controlled.
  • Use of any supplement that may significantly affect cognitive functioning during the month prior to study initiation.
  • Use of any experimental medication within 1 month prior to screening or as concomitant medications.
  • History of hypersensitivity or allergy to soy or fish.

Key Trial Info

Start Date :

August 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2009

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00719953

Start Date

August 1 2008

End Date

August 1 2009

Last Update

April 20 2010

Active Locations (1)

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1

Suorasky Medical Center

Tel Aviv, Israel