Status:

COMPLETED

Calibration and Validation of the STISIM Driving Simulator

Lead Sponsor:

Utrecht Institute for Pharmaceutical Sciences

Conditions:

Simulated Driving Performance

Eligibility:

All Genders

21-50 years

Phase:

NA

Brief Summary

The aim of this study is to calibrate the STISIM driving simulator under influence of three different dosages of ethanol (0.05%, 0.08% and 0.11% BAC). The levels of performance decrement for the three...

Eligibility Criteria

Inclusion

  • 21-50 years old
  • Written informed consent
  • Normal static binocular acuity, corrected or uncorrected
  • Normal hearing
  • Social Drinker (average of 7 to 21 alcoholic drinks per week and experience with drinking 4-6 drinks per occasion)
  • No current or past drug use
  • Possession of a driver's license for at least 3 years
  • Be considered as reliable and mentally capable of adhering to the protocol

Exclusion

  • Current and past drug use (positive urine drug screen on the presence of amphetamines (including MDMA), barbiturates, cannabinoids, benzodiazepines, cocaine, and opiates)
  • Positive urine pregnancy screen in women
  • Present use of psychoactive medication
  • Positive alcohol breath test
  • Prior enrollment in the same study
  • Physical or mental illness
  • Excessive alcohol use ( \> 21 alcoholic drinks per week)
  • Excessive smoking (more than 10 cigarettes per day)
  • Intake of caffeine-containing beverages over 5 glasses per day
  • Simulator sickness, as determined during the training session

Key Trial Info

Start Date :

June 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2009

Estimated Enrollment :

27 Patients enrolled

Trial Details

Trial ID

NCT00720551

Start Date

June 1 2008

End Date

February 1 2009

Last Update

February 13 2009

Active Locations (1)

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1

Utrecht University, Section Psychopharmacology

Utrecht, Netherlands, 3508 TB