Status:

COMPLETED

Study Evaluating the Safety and Pharmacokinetics (PK) of Ascending Single IV Doses of ERB-257 in Healthy Japanese Males

Lead Sponsor:

Wyeth is now a wholly owned subsidiary of Pfizer

Conditions:

Healthy Subjects

Eligibility:

MALE

20-50 years

Phase:

PHASE1

Brief Summary

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of IV administered ERB-257 as single ascending doses to healthy Japanese male subjects

Eligibility Criteria

Inclusion

  • Healthy Japanese men between the ages of 20 and 50.
  • Body mass index (BMI) in the range of 17.6 to 26.4 kg/m2 and body weight greater than or equal to 45 kg2.
  • Have a high probability for compliance with and completion of the study.

Exclusion

  • Presence or history of any disorder that may prevent the successful completion of the study.
  • Acute disease state (eg, nausea, vomiting, infection, fever, or diarrhea) within 7 days before study day 1.

Key Trial Info

Start Date :

October 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2008

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT00722202

Start Date

October 1 2008

End Date

November 1 2008

Last Update

April 28 2009

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

Sekino Clinical Pharmacology Clinic

Tokyo, Japan, 1710014