Status:
COMPLETED
Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome
Lead Sponsor:
Brigham and Women's Hospital
Collaborating Sponsors:
Boston Children's Hospital
Conditions:
Marfan Syndrome
Eligibility:
All Genders
25+ years
Phase:
PHASE3
Brief Summary
Marfan syndrome is an inherited connective tissue disorder with morbidity and mortality from aortic dilation and dissection. The degree of aortic dilation and response to beta-blockade (standard of ca...
Detailed Description
Please See Summary.
Eligibility Criteria
Inclusion
- Age greater than 25 years
- Clinical Marfan Syndrome
Exclusion
- Previous aortic or cardiac surgery
- Pregnancy
- Renal Insufficiency
- Medication intolerance
Key Trial Info
Start Date :
October 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00723801
Start Date
October 1 2007
End Date
December 1 2012
Last Update
September 9 2014
Active Locations (1)
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1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115