Status:
COMPLETED
Effect of I/R Injuries by Pringle Manoeuvre on the Prognosis of HCC Patients After Curative Hepatectomy
Lead Sponsor:
Southwest Hospital, China
Collaborating Sponsors:
Chinese PLA General Hospital
Fudan University
Conditions:
Hepatocellular Carcinoma
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This is a multi-centre prospective randomized controlled trial to explore the influence of ischemia-reperfusion injuries elicited by pringle manoeuvre during radical excision on the prognosis of Hepat...
Detailed Description
Until now there are two popular procedures during the radical excision of primary liver cancer in our country.One is to give a pringle manoeuvre to control the operative blood loss,the other is using ...
Eligibility Criteria
Inclusion
- Clinical diagnosis of resectable primary liver cancer
- The liver function showed:Child-Pugh A，ICG-R15 \< 20%
- HbsAg (+)
- tumor nodes in the liver were singular or multiple and could be radical excision
- No preoperative anti-cancer therapy
- Written informed consent from the patient or legal guardian prior to entering the study
Exclusion
- Pregnancy patients
- With extrahepatic tumor or lymphnode metastasis
- Tumor invasion or thrombosis in portal vein,hepatic vein or inferior vena cava
- Positive marginal
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2012
Estimated Enrollment :
498 Patients enrolled
Trial Details
Trial ID
NCT00725335
Start Date
September 1 2008
End Date
November 1 2012
Last Update
November 27 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Institute of hepatobiliary surgery,southwest hospital
Chongqing, Chongqing Municipality, China, 400038