Status:
UNKNOWN
China Intensive Lipid Lowering With Statins in Acute Coronary Syndrome
Lead Sponsor:
Ministry of Science and Technology of the People´s Republic of China
Conditions:
Acute Coronary Syndrome
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
In summary, the CHILLAS study will be the first multicenter study performed in a Chinese population using a patient-level analysis to compare the effects and safety of intensive statin therapy with th...
Detailed Description
The CHILLAS study is planned to evaluate whether intensive treatment with statins for 2 years results in a reduction of cardiovascular events in patients with ACS. A total of 1,600 patients will be ra...
Eligibility Criteria
Inclusion
- Clinical diagnosis of acute coronary syndrome
- Clinically stable for 24 hours
Exclusion
- Hypersensitive to statins
- Receiving therapy with atorvastatin at a dose greater than 20 mg per day before enrollment or lipid-lowering therapy with fibric acid derivatives or niacin that can not be discontinued
- Having a coexisting condition that shortened expected survival to less than two years
- Having obstructive hepatobiliary disease or other serious hepatic or kidney disease
- Having an unexplained elevation in the creatine kinase level that was more than three times the upper limit of normal and that was not related to myocardial infarction
- Having undergone surgery or serious trauma within the preceding two months
- Having been in the final stage of chronic congestive heart failure
- Having a baseline level of LDL cholesterol less than 50mg/dl
Key Trial Info
Start Date :
December 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2010
Estimated Enrollment :
1600 Patients enrolled
Trial Details
Trial ID
NCT00728013
Start Date
December 1 2006
End Date
December 1 2010
Last Update
August 25 2008
Active Locations (1)
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1
The Second Xiangya Hospital of Central South University
Changsha, Hunan, China, 410011