Status:
COMPLETED
Evaluation and Standardization of Ginseng and it's Components for Blood Pressure Regulation
Lead Sponsor:
Unity Health Toronto
Collaborating Sponsors:
Heart and Stroke Foundation of Canada
Conditions:
Hypertension
Blood Pressure
Eligibility:
All Genders
18-70 years
Phase:
PHASE2
Brief Summary
Ginseng has been used for many years in a wide array of anecdotal medicinal properties. Animal and limited clinical research points to the vascular effects of Korean Red Ginseng (KRG). The present pro...
Eligibility Criteria
Inclusion
- Age: between 18 and 70 years of age
- Healthy individuals (absence of major illnesses)
Exclusion
- Primary hypertension (defined by the use of antihypertensive agents or a seated systolic blood pressure greater than or equal to 140mmHg or diastolic blood pressure greater than 90mmHg)
- Secondary hypertension (defined as SBP greater than 180mmHg and DBP greater than 110mmHg)
- Grade 3 hypertension (defined as SBP greater than 180mmHg and DBP greater than 110mmHg)
- Diabetes
- Chronic kidney disease
- Liver disease
- Estrogen-sensitive cancer
- Heavy alcohol use
- Bleeding disorders
- Planned surgery
- Angina
- CHF
- Coronary revascularization
- Peripheral vascular disease
- Coronary/cerebrovascular event in the last 6 months
- Prescriptions of MAO inhibitors, SSRIs, diuretics, sympathomimetics, herbal therapies, medication affecting nitric oxide synthesis, and/or anticoagulent medications within the last 6 months
- Sensitivity to any of the ingredients in the treatments or placebo
- Chronic use of or frequent prescriptions for NSAIDs
- Women of childbearing potential must not be pregnant or breast-feeding
Key Trial Info
Start Date :
November 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2008
Estimated Enrollment :
17 Patients enrolled
Trial Details
Trial ID
NCT00728221
Start Date
November 1 2007
End Date
April 1 2008
Last Update
January 6 2017
Active Locations (1)
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1
St. Michael's Hospital Clinical Nutrition and Risk Factor Modification Centre
Toronto, Ontario, Canada, M5C 1N8